Firstly and most importantly, Abiraterone Acetate 250mg is indicated for use in combination with prednisone for the treatment of men therefore with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel.
However, Abiraterone Acetate is Given as follows:
- Abiraterone acetate is a pill, taken by mouth.
- It must be taken on an empty stomach [however, 2 hours after a meal or one hour before]
- Prednisone [10mg daily] should be taken along with abiraterone acetate.
- Moreover, The amount of abiraterone acetate you receive depends on many factors. Your doctor will determine your dose and schedule
Abiraterone Acetate 250mg Side Effects:
- Most people will not experience all of the abiraterone acetate side effects listed.
- Therefore, there are many options to minimize or prevent the side effects of abiraterone acetate.
- Fluid Retention
- Increased triglycerides
- Increased liver enzymes (AST)
- Joint swelling/discomfort
- Decreased levels of potassium in your blood (hypokalemia)
- Peripheral Edema (swelling of the hands/feet)
- Muscle aches/discomfort
- Decreased levels of phosphorus in your blood (hypophosphatemia)
- Hot flashes
- Urinary tract infections
- Increased ALT (liver enzyme)
Moreover, Abiraterone acetate works by inhibiting specific “enzymes” in your adrenal glands that are responsible for making androgens. For this reason, there is an increased risk of overproduction of mineral corticosteroids in your body while on abiraterone acetate. As a result, abiraterone acetate may cause hypertension [high blood pressure], hypokalemia [low levels of potassium in the blood], and fluid retention. Hence, Dosing along with prednisone will decrease the risk of mineralocorticoid excess.
When to contact your physician or health care provider:
Therefore, Contact the physician in case you are suffering from such symptoms :
- Fever of 100.4° F (38° C or higher, chills)
- Chest Pain or Irregular heartbeats
- Difficulty breathing
- Inability to urinate for 8 or more hours
- Dizziness / Lightheadedness
- Significant headache
- Diarrhea (4-6 episodes in a 24-hour period)
- Unusual bleeding or bruising
- Black or tarry stools, or blood in your stools
- Extreme fatigue (unable to carry on self-care activities)
- Yellow coloring of your skin or eyes
- Unusual elevation in blood pressure
Abiraterone Acetate Precautions:
- Before starting abiraterone acetate treatment, make sure you tell your doctor about any other medications. However, you are taking (however, including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take aspirin, products containing aspirin unless your doctor specifically permits this.
Abiraterone Acetate Self-Care Tips:
Therefore here are some self-care tips as follows :
- You will need to continue receiving your LHRH/GnRH agonists injections (ie Zoladex®, Lupron®, Trelstar®, etc) throughout treatment with abiraterone acetate.
- If you are experiencing hot flashes, wear light clothing, stay in a cool environment to try and reduce symptoms. Therefore, Consult your healthcare provider if these worsen or become intolerable.
- You should discuss this with your doctor.
- Get plenty of rest.
- Maintain good nutrition.
- However, If you experience symptoms or side effects, be sure to discuss them with your health care team. In other words, They can prescribe medications and/or offer other suggestions that are effective in managing such problems.
How Abiraterone Acetate Works:
Moreover, Hormone therapy can work by stopping the production of a certain hormone, blocking hormone receptors or substituting chemically similar agents for the active hormone. However, which cannot be used by the tumour cell. Decreasing the production of these hormones is critical in helping men fight prostate cancer.
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